ZANAFLEX DRUG INFO

IMPORTANT NOTE: The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug.

TIZANIDINE - ORAL (tize-AN-ih-deen)

COMMON BRAND NAME(S): Zanaflex

USES: This medication is used to treat muscle spasms.

ZANAFLEX USAGE: Take Zanaflex exactly it has been recommended by your physician. If you do not understand these instructions, ask your pharmacist, nurse, or doctor to explain them to you. Take each dose with a full glass of water. Zanaflex is usually taken several times a day. Follow your doctor's instructions. Do not take more than three doses of tizanidine--or more than 36 mg--within a 24 period. Too much of this medication has the potential to damage your liver. Store Zanaflex at room temperature away from moisture and heat.

SIDE EFFECTS: Nausea, drowsiness, dizziness, constipation, unusual weakness or dry mouth might occur. If these continue or are bothersome, notify your doctor. To minimize dizziness, stand up slowly when arising from a sitting or lying position. Notify your doctor if you develop: yellowing skin or eyes (or a jaundice type appearance), stomach pain, vomiting, hallucinations. Very unlikely but report: vision or hearing changes, urinary frequency or burning, slow or irregular heartbeat, black stool. An allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of an allergic reaction include rash, itching, dizziness, trouble breathing. If you notice other effects not listed above, contact your doctor or pharmacist.

PRECAUTIONS: Before taking Zanaflex , tell your doctor if you have: any allergies, significantly low blood pressure, liver or heart disease, kidney disease, eye disease. Limit the use of alcohol as alcohol may intensify the dizziness and drowsiness effects of this drug. Use caution when driving or operating machinery or when alertness is required. This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor. It is currently unknown whether this drug is excreted into human milk. Consult your doctor before breast-feeding. Caution is advised when this drug is used in the elderly.

DRUG INTERACTIONS:Be sure to inform your doctor of all prescription and nonprescription medications you may take, especially of: blood pressure drugs (e.g., water pills, clonidine, methyldopa, guanabenz, guanfacine), MAO inhibitors (e.g., linezolid, furazolidone, phenelzine, selegiline), sleep enhancement medicines, sedatives (e.g., diazepam), tranquilizers, anti-anxiety drugs, narcotic pain relievers (e.g., codeine, morphine), barbiturates (e.g., phenobarbital), certain antihistamines (e.g., diphenhydramine), other muscle relaxants (e.g., cyclobenzaprine), certain antidepressants (e.g., imipramine, amitriptyline, trazodone), phenothiazine psychiatric drugs (e.g., chlorpromazine), birth control pills. Do not start or stop any medicine without doctor or pharmacist approval.

OVERDOSE: If overdose of this medication is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include trouble breathing or unconsciousness.

NOTES: Your doctor may monitor liver tests during treatment. Do not share this medication with others.

MISSED DOSE: If you miss a dose of Zanaflex, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not "double-up" the dose to catch up.

STORAGE: Store at room temperature between 59 and 86 degrees F (15-30 degrees C) away from light and moisture.

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